The long-standing silence has been shattered. John Stamos, in a recent explosive podcast appearance, has come forward to vehemently defend his "Full House" co-star Lori Loughlin, attributing her involvement in the notorious Operation Varsity Blues college admissions scandal and the subsequent crumbling of her marriage to her husband, Mossimo Giannulli.

In the emotionally charged October 20, 2025, episode of the "Good Guys" podcast, Stamos laid bare his perspective, labeling Giannulli a "terrible narcissist" and pinning him as the mastermind behind the scandal that led to prison sentences for both Giannulli and Loughlin. "Forty years I’ve known her," Stamos recounted, his voice heavy with emotion. "This woman’s a saint. I’m just heartbroken for her right now."

The saga took a fresh twist with Stamos revealing a critical conversation he had with Loughlin when the charges were first made public in March 2019. According to Stamos, Loughlin expressed her shock and claimed ignorance, stating, "Mossimo handles all that stuff." This revelation paints a stark picture of Loughlin's alleged limited involvement and places significant blame squarely on Giannulli.

The scandal's impact has been profound and far-reaching, not only leading to legal repercussions but also causing the disintegration of Loughlin and Giannulli’s 27-year marriage. Representatives for Loughlin confirmed the couple are now living apart, with no current legal proceedings for divorce filed yet. Stamos described this new development as another layer of heartbreak for Loughlin, witnessing her family's public and painful unraveling.

While the public may be swayed by Stamos's heartfelt defense and the narrative of Giannulli’s overwhelming influence, it is essential to remember that both Loughlin and Giannulli pleaded guilty to charges including conspiracy to commit wire and mail fraud. They faced serious legal penalties, with Loughlin serving two months and Giannulli five months in federal prison.

Legal experts emphasize the severity and clarity of the federal laws violated by the couple. Silva Megerditchian, a criminal defense attorney, remarked on the efficiency of federal prosecutors, highlighting the real consequences faced when such charges are brought forth.

As Stamos continues to advocate for Loughlin’s character and innocence, the legal facts remain unchangeable. Both parties were involved, pleaded guilty, and served time — a somber reminder of the consequences of attempting to manipulate institutional systems. The scandal not only altered their personal lives but also served as a cautionary tale about the perils of overstepping legal boundaries, no matter the intentions or the individuals involved.